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Robson, Noorzurani and Bond, A. J. and Wolff, K. (2010) Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva. African Journal of Pharmacy and Pharmacology, 4 (2). pp. 61-65. ISSN 1996-0816

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    Abstract

    Salivary nicotine and salivary cotinine is widely used in clinical and epidemiological studies to validate smoking cessation. However, the reported collection for salivary nicotine and salivary cotinine vary by technique and duration. This study investigated the influence of salivary collection by unstimulation and stimulation technique of the concentration of salivary nicotine and salivary cotinine. It was found that unstimulated technique produced the highest salivary nicotine concentration, whereas stimulated technique produced the highest salivary cotinine concentration. The results of this study suggest that it is important to standardise salivary nicotine and cotinine collection technique.

    Item Type: Article
    Uncontrolled Keywords: Saliva, smoker, nicotine, cotinine, technique, biological marker, oral, verify, passive, tobacco, smoke, flow-rate, clinical-pharmacology, exposure, smoking, absorption, plasma, urine
    Subjects: Medicine and Dentistry > Clinical Medicine
    Divisions: UNSPECIFIED
    Depositing User: Noorzurani Robson
    Date Deposited: 13 May 2012 13:14
    Last Modified: 13 May 2012 13:14
    URI: http://opendepot.org/id/eprint/1107

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