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Zanaruddin, S. N. S. and Cheong, S. C. and Rahman, Z. A. A. and Ghani, Wmnw Abd and Mustafa, W. M. W. and Zain, R. B. and Kong, Y. H. and Hor, S. Y. and Teo, S. H. (2011) High throughput mutational profiling of signaling molecules in oral cancer. Oral Oncology, 47. S115-S115. ISSN 1368-8375

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      It is well established that a plethora of mutations that occur in oncogenes and tumor-suppressor genes are the main drivers of tumorigenesis. The identification of these mutations provides important clues to the cellular processes of carcinogenesis and affords an opportunity for these genes to be used for diagnostic and therapeutic purposes. In comparison to cancers such as breast, lung and colorectal, there is a lack of systematic, large scale characterization of oncogenic mutations oralsquamous cell carcinoma (OSCC).

      Item Type: Article
      Uncontrolled Keywords: Oral squamous cell carcinoma, OSCC, lichenoid lesions, lichen planus, oral cancer, oral tumours, pemphigus, traumatic eosinophilic granuloma, aphthous ulcers, oral mucosal lesions, betel chewers mucosa, betel quid related lesions, betel quid, areca quid, tobacco quid, oral cancer screening, training and calibration, early detection, oral cancer awareness, biobanking, tissue bank, databank, oral cancer, tissue bank, research credibility, research ethics.
      Subjects: Medicine and Dentistry
      Divisions: UNSPECIFIED
      Depositing User: Prof. Dr. Rosnah Mohd Zain
      Date Deposited: 03 Feb 2012 01:24
      Last Modified: 03 Feb 2012 01:24
      URI: http://opendepot.org/id/eprint/625

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