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Robson, Noorzurani and Bond, A. J. and Wolff, K. (2012) Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva. African Journal of Pharmacy and Pharmacology, 4 (2). pp. 61-65. ISSN 1996-0816

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    Salivary nicotine and salivary cotinine is widely used in clinical and epidemiological studies to validate smoking cessation. However, the reported collection for salivary nicotine and salivary cotinine vary by technique and duration. This study investigated the influence of salivary collection by unstimulation and stimulation technique of the concentration of salivary nicotine and salivary cotinine. It was found that unstimulated technique produced the highest salivary nicotine concentration, whereas stimulated technique produced the highest salivary cotinine concentration. The results of this study suggest that it is important to standardise salivary nicotine and cotinine collection technique.

    Item Type: Article
    Uncontrolled Keywords: Saliva smoker nicotine cotinine technique biological marker oral verify passive tobacco smoke flow-rate clinical-pharmacology exposure smoking absorption plasma urine
    Subjects: Medicine and Dentistry > Clinical Medicine
    Divisions: UNSPECIFIED
    Depositing User: Noorzurani Robson
    Date Deposited: 09 Mar 2012 02:30
    Last Modified: 09 Mar 2012 02:31
    URI: http://opendepot.org/id/eprint/778

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